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Article

Antigen-resolved remodeling of EBV-specific CD8⁺ T cell immunity in multiple sclerosis

2026-06-01

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis (MS) is strongly linked to Epstein-Barr Virus (EBV) infection, yet how antiviral immunity contributes to disease pathogenesis remains unclear. Here we delineate EBV-specific CD8+ T cell responses at antigen and single cell resolution in treatment-naïve people with MS. This analysis reveals selective expansion of CD8+ T cells directed to EBV-encoded latent antigens, in...

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Literature Corpus work
30e3f31b-fbdb-5b7d-9941-96825dc1f13a
DOI
10.21203/rs.3.rs-9686341/v1
Open publication

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Antigen-resolved remodeling of EBV-specific CD8⁺ T cell immunity in multiple sclerosisDOI 10.21203/rs.3.rs-9686341/v1
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