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Article

Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis.

Frontiers in immunology - 1 Jan 2021

Meier Ute-Christiane, Cipian Richard Christopher, Karimi Abbas, Ramasamy Ranjan, Middeldorp Jaap Michiel

Abstract excerpt

Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating virus with major immunogenic influences and a near 100% epidemiological association with MS, is considered to play a leading role in MS pathogenesis, triggering...

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Identifiers

PMID: 34790199
DOI: 10.3389/fimmu.2021.757302
PMCID: PMC8592026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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