Article

Mapping of CD8 T-cell recognition to latent EBV infection and neuroantigens reveals HLA-specific depletion of T-cell responses in multiple sclerosis

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Multiple sclerosis (MS) is a complex autoimmune disease with an unclear contribution from antigen-specific CD8 T cells. To enumerate adaptive immune responses associated with MS and to identify MS-related epitopes recognized by CD8 T cells, we evaluated T-cell recognition of 1,158 predicted major histocompatibility complex (MHC)-binding peptides derived from latent EBV antigens (laEBVs) and sele...

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Literature Corpus work: 2bff4eb4-ebd9-55db-8532-0244a6692bb5
DOI: 10.1101/2025.10.23.682742

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