Article

Adoptive T-Cell Therapy for Solid Tumors

2017-01-01

Abstract excerpt

Chimeric antigen receptor (CAR) T-cell therapy is an innovative form of immunotherapy wherein autologous T cells are genetically modified to express chimeric receptors encoding an antigen-specific single-chain variable fragment and various costimulatory molecules. Upon administration, these modified T cells traffic to, and recognize, cancer cells in an HLA-independent manner. CAR T-cell therapy has shown remarkabl...

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CAR-T cell therapy research

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Literature Corpus work: 30bb8a76-7877-5729-8b25-44925398f9ec
DOI: 10.14694/edbk_180328

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