Article

Whole-genome sequencing of a multiple endocrine neoplasia type 1 proband identifies gross deletion in MEN1

2020-02-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant tumor syndrome with neuroendocrine tumorigenesis of the parathyroid and pituitary glands and pancreatic islet cells. This hereditary cancer is caused by germline mutations in the <italic>MEN1</italic>, located on chromosome 11q13. Among the approximately 3,000 cancer patients, in which multi-omics...

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Literature Corpus work: 3050746d-64a7-5d92-ba91-acff97b658d6
DOI: 10.21203/rs.2.23794/v1

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