Article
Multiple endocrine neoplasia type 1: new clinical and basic findings.
Trends in endocrinology and metabolism: TEM - 1 Jan 2000
Schussheim D H, Skarulis M C, Agarwal S K, Simonds W F, Burns A L, Spiegel A M, Marx S J
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1) provides a prime example of how a rare disease can advance our understanding of basic cell biology, neoplasia and common endocrine tumors. MEN1 is expressed mainly as parathyroid, enteropancreatic neuroendocrine, anterior pituitary and foregut carcinoid tumors. It is an autosomal dominant disease caused by mutation of the MEN1 gene. Since its identification, the MEN1...
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