Article
Multiple endocrine neoplasia type 1 (MEN1): not only inherited endocrine tumors.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Dec 2009
Falchetti Alberto, Marini Francesca, Luzi Ettore, Giusti Francesca, Cavalli Loredana, Cavalli Tiziana, Brandi Maria Luisa
Abstract excerpt
MEN 1 is a rare hereditary cancer syndrome which manifests a variety of endocrine and non-endocrine neoplasms and lesions. Growing knowledge of this condition in both its molecular genetic underpinnings and its clinical implications have affected the entire spectrum of the clinical management of MEN patients. The MEN1 gene is a tumor suppressor gene, and mutations in it account for the development of the MEN1...
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