Genomic profiling of multiple tissues in two patients with multiple endocrine neoplasia type 1.

doi:10.2220/biomedres.42.89

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genomic profiling of multiple tissues in two patients with multiple endocrine neoplasia type 1.

Biomedical research (Tokyo, Japan) - 1 Jan 2021

Naruoka Akane, Ohnami Sumiko, Nagashima Takeshi, Serizawa Masakuni, Hatakeyama Keiichi, Ohshima Keiichi, Ohnami Shumpei, Urakami Kenichi, Horiuchi Yasue, Kiyozumi Yoshimi, Matsubayashi Hiroyuki, Abe Masato, Ohishi Takuma, Kameya Toru, Sugino Takashi, Onitsuka Tetsuro, Isaka Mitsuhiro, Ohde Yasuhisa, Sugiura Teiichi, Ito Takaaki, Uesaka Katsuhiko, Akiyama Yasuto, Kusuhara Masatoshi, Yamaguchi Ken

Abstract excerpt

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant tumor syndrome. This hereditary cancer is caused by germline variants in MEN1. Two patients with MEN1 were identified via whole exome sequencing and gene expression profile analysis, conducted for 5,063 patients with various types of cancers. We obtained multiple tumors from each patient; tumors derived from these two MEN1 patients had a loss of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Rearrangement

Share to Genome, Human

Share to Genomics

Share to Multiple Endocrine Neoplasia Type 1

Share to Neuroendocrine Tumors

Share to Proto-Oncogene Proteins

Source

Open in PubMed

Identifiers

PMID: 33840689
DOI: 10.2220/biomedres.42.89

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic profiling of multiple tissues in two patients with multiple endocrine neoplasia type 1.PMID 33840689Read ↗

Whole-genome sequencing of a multiple endocrine neoplasia type 1 proband identifies gross deletion in MEN1Semantic proximity Read ↗

Multiple endocrine neoplasia type 1 (MEN1): not only inherited endocrine tumors.Semantic proximity Read ↗

Identification of Novel Variants in MEN1: A Study Conducted with Four Multiple Endocrine Neoplasia Type 1 Patients.Semantic proximity Read ↗

Clinical and molecular diagnosis of multiple endocrine neoplasia type 1.Semantic proximity Read ↗

Germline MEN1 mutations in sixteen Japanese families with multiple endocrine neoplasia type 1 (MEN1).Semantic proximity Read ↗

Two distinct classes of thymic tumors in patients with MEN1 show LOH at the MEN1 locusSemantic proximity Read ↗

Germline and somatic mosaicism in a family with multiple endocrine neoplasia type 1 (MEN1) syndromeSemantic proximity Read ↗

Multiple endocrine neoplasia type 1 (MEN1): An update of 208 new germline variants reported in the last nine yearsSemantic proximity Read ↗

Systematic detection of mosaicism by using digital NGS reveals three new MEN1 mosaicismsSemantic proximity Read ↗

Multiple Endocrine Neoplasia Type 1: Latest InsightsSemantic proximity Read ↗

Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's oldSemantic proximity Read ↗

Five novel mutations in the familial multiple endocrine neoplasia type 1 (MEN1) gene. Mutations in brief no. 188. Online.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.