Article

Super-Enhancer Network in Metastatic Prostate Cancer: A Bioinformatics and Experimental Approach

2025-12-18

Abstract excerpt

<title>Abstract</title> <p> Prostate cancer (PC) metastasis poses a critical therapeutic challenge, driven in part by dysregulated transcriptional landscapes governed by super-enhancers (SEs). This study combines integrative bioinformatics and experimental validation to uncover SE-associated hub genes implicated in metastatic PC. RNA-seq datasets from metastatic PC cell lines (PC3 and DU-145) treated with the BE...

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Literature Corpus work: 304eda40-cdd9-5ba2-975b-23a4bc940b91
DOI: 10.21203/rs.3.rs-8327156/v1

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