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Image-based profiling of healthy donor immune cells with Blood Cell Painting reveals novel genotype-phenotype associations

2024-05-19

Abstract excerpt

The morphological diversity of blood immune cells of healthy individuals, critical for recognizing disease-related phenotypes, remains largely uncharacterized. To address this gap, we developed Blood Cell Painting (BCP): a high content, high throughput fluorescence imaging assay for peripheral blood mononuclear cells. We generated a BCP Atlas with images of 50 million cells from 390 healthy blood donors, identifyi...

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Literature Corpus work
2fef350c-aece-5b8b-8c0e-9681506ad1dc
DOI
10.1101/2024.05.17.594648
Open publication

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Image-based profiling of healthy donor immune cells with Blood Cell Painting reveals novel genotype-phenotype associationsDOI 10.1101/2024.05.17.594648
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