Article

Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

2020-01-31

Abstract excerpt

<h4>SUMMARY</h4> Thousands of genetic associations with phenotypes of blood cells are known, but few are with phenotypes relevant to cell function. We performed GWAS of 63 flow-cytometry phenotypes, including measures of cell granularity, nucleic acid content, and reactivity, in 39,656 participants in the INTERVAL study, identifying 2,172 variant-trait associations. These include associations mediated by function...

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Literature Corpus work: 2662fbbc-9b41-57ec-b83e-17844ea58680
DOI: 10.1101/2020.01.30.927483

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