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Article

MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET Database

3 Nov 2017

Abstract excerpt

Purpose RNA and DNA sequencing data are traditionally used to discern intrinsic cellular pathways in cancer pathogenesis, their utility for investigating the tumor microenvironment has not been fully explored. This study explores the use of sequencing data to investigate immunity within the tumor microenvironment. Experimental design Here we use immune cell fraction estimation analysis to determine the immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29163537
DOI: 10.3389/fimmu.2017.01473

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