Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of MS risk genes and pathways at distinct stages of disease

17 Mar 2017

Abstract excerpt

OBJECTIVE: To perform systematic transcriptomic analysis of multiple sclerosis (MS) risk genes in peripheral blood mononuclear cells (PBMCs) of subjects with distinct MS stages and describe the pathways characterized by dysregulated gene expressions. METHODS: We monitored gene expression levels in PBMCs from 3 independent cohorts for a total of 297 cases (including clinically isolated syndromes (CIS),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Genetic Neurodegenerative Diseases
Share to Multiple Sclerosis Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28349074
DOI: 10.1212/nxi.0000000000000337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of MS risk genes and pathways at distinct stages of diseasePMID 28349074Read ↗

Global transcriptome profiling of mild relapsing‐remitting versus primary progressive multiple sclerosisSemantic proximity Read ↗

Multiple Sclerosis Stages and their Differentially Expressed Genes: A Bioinformatics AnalysisSemantic proximity Read ↗

Integrating genome-wide association studies and gene expression data highlights dysregulated multiple sclerosis risk pathways.Semantic proximity Read ↗

Immune Cell Heterogeneity in Multiple Sclerosis Reveals Myeloid-Specific Dysfunction and Distinct Regulatory Programs Across CD14+, CD4+, and CD8+ Immune CellsSemantic proximity Read ↗

Integrative analysis of Multiple Sclerosis using a systems biology approachSemantic proximity Read ↗

The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis.Semantic proximity Read ↗

Gene Expression and Alternative Splicing Analysis in a Large-Scale Multiple Sclerosis Study.Semantic proximity Read ↗

Gene expression and alternative splicing analysis in a large-scale Multiple Sclerosis studySemantic proximity Read ↗

Unveiling the Molecular Landscape: Network Analysis of Genes, Proteins, and Transcription Factors in Primary Progressive and Secondary Progressive Multiple Sclerosis for Unraveling Disease Progression and Prognostic FactorsSemantic proximity Read ↗

Comparing Single-Cell Transcriptomes of Blood and Cerebrospinal Fluid Leukocytes in Multiple SclerosisSemantic proximity Read ↗

Whole transcriptome analysis of multiple Sclerosis patients reveals active inflammatory profile in relapsing patients and downregulation of neurological repair pathways in secondary progressive casesSemantic proximity Read ↗

Genetic and gene expression signatures in multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.