Article

A Preclinical Model of Cutaneous Melanoma Based on Reconstructed Human Epidermis

2022-01-14

Abstract excerpt

Malignant melanoma is among the tumor entities with the highest increase of incidence worldwide. To elucidate melanoma progression and develop new effective therapies, rodent models are commonly used. While these do not adequately reflect human physiology, two-dimensional cell cultures lack crucial elements of the tumor microenvironment. To address this shortcoming, we have developed a melanoma skin equivalent bas...

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Literature Corpus work: 2fc69fbb-48d0-5c95-92ac-fcc47c271f6e
DOI: 10.21203/rs.3.rs-1193450/v1

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