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Article

Investigating the utility of human melanoma cell lines as tumour models.

Oncotarget - 7 Feb 2017

Vincent Krista Marie, Postovit Lynne-Marie

Abstract excerpt

Melanoma researchers utilize cell lines to model many tumour phenomena. It is thus important to understand similarities and differences between cell lines and the tumours that they represent, so that the optimal models can be chosen to answer specific research questions. Herein, we compared the transcriptomes of 42 melanoma cell lines to hundreds of tumours from The Cancer Genome Atlas and thousands of single...

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Identifiers

PMID: 28060736
DOI: 10.18632/oncotarget.14443
PMCID: PMC5354675

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