Article

Developing a melanoma-skin-on-a-chip integrated with vasculature using an edgeless skin reconstruction approach

2026-06-29

Abstract excerpt

<title>Abstract</title> <p> Melanoma is the most aggressive form of skin cancer, characterized by high metastatic potential and frequent resistance to targeted therapies. Traditional 2D cultures and animal models often fail to accurately mimic the complexity of the human tumor microenvironment (TME). To improve the recapitulation of the cellular and mechanical microenvironmental cues, we bioengineered a melanoma...

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Literature Corpus work: 9b7242a9-8aea-508d-a8d3-97e49813e22d
DOI: 10.21203/rs.3.rs-10045259/v1

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