Article

Melanoma Brain Metastases Patient-Derived Organoids: an <em>in Vitro</em> Platform for Drug Screening

2024-07-08

Abstract excerpt

<h4>Background: </h4> and aims: Brain metastases are prevalent in the late stages of malignant melanoma. Multimodal therapy remains challenging. Patient-derived organoids (PDOs) represent a valuable pre-clinical model, faithfully recapitulating key aspects of the original tumor, including the heterogeneity and the mutational status. This study aimed to establish PDOs from melanoma brain metastases (MBM-PDOs) and t...

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Literature Corpus work: fa547d8f-d0cc-526e-a5a6-37b0904a4d53
DOI: 10.20944/preprints202407.0598.v1

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