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Article

Exploring the Dynamics and Mutational Landscape of Riboregulation with a Minimal Synthetic Circuit in Living Cells.

Biophysical journal - 1 Sept 2015

Rodrigo Guillermo, Majer Eszter, Prakash Satya, Daròs José-Antonio, Jaramillo Alfonso, Poyatos Juan F

Abstract excerpt

The regulation of gene expression, triggered by conformational changes in RNA molecules, is widely observed in cellular systems. Here, we examine this mode of control by means of a model-based design and construction of a fully synthetic riboregulatory device. We present a theoretical framework that rests on a simple energy model to predict the dynamic response of such a system. Following an equilibrium...

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Identifiers

PMID: 26331264
DOI: 10.1016/j.bpj.2015.07.021
PMCID: PMC4564674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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