Article

Functional stemness-related genes revealed by single-cell profiling of naïve and stimulated human CD34 + cells from CB and mPB

2022-04-25

Abstract excerpt

Hematopoietic stem cells (HSCs) from different sources show varied repopulating capacity, and HSCs lose their stemness after long-time ex vivo culture. However, the underlying mechanisms of the stemness differences because of the cell sources and the culture stimulation are not fully understood. Here, we applied single-cell RNA-seq (scRNA-seq) to analyze the naïve and stimulated human CD34 + cells from cord blood...

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Literature Corpus work: 2f290fc8-5cbe-5b11-81ba-8c90b3e7006b
DOI: 10.21203/rs.3.rs-1571273/v1

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