Article

Mapping the human hematopoietic stem and progenitor cell hierarchy through integrated single-cell proteomics and transcriptomics

2024-07-06

Abstract excerpt

<h4>Summary</h4> Single-cell transcriptomics (scRNA-seq) has enabled the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, since proteins are the main functional entities in cells, the exclusive use of mRNA measurements comes at the risk of missing important biological information. Here we leverage recent technological advances in single-cell proteomics by M...

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Literature Corpus work: ca0aa97c-f230-5909-9a0e-99111b30a77d
DOI: 10.1101/2024.07.05.602277

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