Article

Functional stemness-related genes revealed by single-cell profiling of naïve and stimulated human CD34 <sup>+</sup> cells from CB and mPB

2022-02-24

Abstract excerpt

Hematopoietic stem cells (HSCs) from different sources show varied repopulating capacity, and HSCs lose their stemness after long-time ex vivo culture. However, the underlying mechanisms of the stemness differences because of the cell sources and the culture stimulation are not fully understood. Here, we applied single-cell RNA-seq (scRNA-seq) to analyze the naïve and stimulated human CD34 + cells from cord bloo...

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Literature Corpus work: 2421165d-697f-5105-90a7-84df9e146247
DOI: 10.1101/2022.02.23.481626

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