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Article

Single-cell evaluation reveals innate immune arrested and lymphocytes shifting that promote development of preinvasive lung adenocarcinoma

2022-02-08

Abstract excerpt

<title>Abstract</title> <p>Cancer immunotherapy has demonstrated promising efficacy in the neoadjuvant setting for treating early-stage non-small cell lung cancer (NSCLC). However, immunotherapy for preinvasive or early invasive disease has been largely overlooked. We performed single-cell RNA and TCR sequencing for 266,804 high quality cells as well as whole exome sequencing (WES) and multiplex immunofluorescenc...

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Literature Corpus work
2f1c7542-eaec-5524-a798-e7824ee0553c
DOI
10.21203/rs.3.rs-1084110/v1
Open publication

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Single-cell evaluation reveals innate immune arrested and lymphocytes shifting that promote development of preinvasive lung adenocarcinomaDOI 10.21203/rs.3.rs-1084110/v1
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