Article
Using genetic variation to disentangle the complex relationship between food intake and health outcomes.
PLoS genetics - 1 Jun 2022
Pirastu Nicola, McDonnell Ciara, Grzeszkowiak Eryk J, Mounier Ninon, Imamura Fumiaki, Merino Jordi, Day Felix R, Zheng Jie, Taba Nele, Concas Maria Pina, Repetto Linda, Kentistou Katherine A, Robino Antonietta, Esko Tõnu, Joshi Peter K, Fischer Krista, Ong Ken K, Gaunt Tom R, Kutalik Zoltán, Perry John R B, Wilson James F
Abstract excerpt
Diet is considered as one of the most important modifiable factors influencing human health, but efforts to identify foods or dietary patterns associated with health outcomes often suffer from biases, confounding, and reverse causation. Applying Mendelian randomization in this context may provide evidence to strengthen causality in nutrition research. To this end, we first identified 283 genetic markers...
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