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Identification of <i>SENP7</i> and <i>UTF1</i> / <i>VENTX</i> as new loci influencing clustered protocadherin methylation across blood and brain using a genome-wide association study

2024-12-21

Abstract excerpt

<h4>Summary</h4> The epigenetic regulation of clustered protocadherin (c PCDH ) genes is tightly linked to their function as specific cell surface barcodes for neural self-nonself discrimination. Differential c PCDH DNA methylation in both blood and brain has been implicated in diverse human traits and diseases ranging from BMI, aging, cancer and brain disorders. However, the unique regulation of c PCDH methyl...

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Literature Corpus work
2ed30cc2-d531-59e3-85d5-236abe0dc1fc
DOI
10.1101/2024.12.19.629385
Open publication

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Identification of <i>SENP7</i> and <i>UTF1</i> / <i>VENTX</i> as new loci influencing clustered protocadherin methylation across blood and brain using a genome-wide association studyDOI 10.1101/2024.12.19.629385
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