Article

Fitness of a clonal population can be inferred from lineage trees without knowledge of the biological details

2022-09-10

Abstract excerpt

Inferring the rate at which a clonal population grows, or its fitness, is important for many biomedical applications. For example, measuring the fitness of mutated cells in a patient with cancer may provide important information about prognosis and treatment. Similarly, measuring the fitness of new viral strains that emerge during a pandemic can inform how to plan an effective response. In previous work, the linea...

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Literature Corpus work: 2ea4c4a3-fb0e-5837-ba60-511ca07457b5
DOI: 10.1101/2022.09.09.507320

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