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Article

Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data.

PLoS genetics - 1 Mar 2017

Nozoe Takashi, Kussell Edo, Wakamoto Yuichi

Abstract excerpt

Recent advances in single-cell time-lapse microscopy have revealed non-genetic heterogeneity and temporal fluctuations of cellular phenotypes. While different phenotypic traits such as abundance of growth-related proteins in single cells may have differential effects on the reproductive success of cells, rigorous experimental quantification of this process has remained elusive due to the complexity of single cell...

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Identifiers

PMID: 28267748
DOI: 10.1371/journal.pgen.1006653
PMCID: PMC5360348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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