Article
Predicting evolution from the shape of genealogical trees.
eLife - 11 Nov 2014
Neher Richard A, Russell Colin A, Shraiman Boris I
Abstract excerpt
Given a sample of genome sequences from an asexual population, can one predict its evolutionary future? Here we demonstrate that the branching patterns of reconstructed genealogical trees contains information about the relative fitness of the sampled sequences and that this information can be used to predict successful strains. Our approach is based on the assumption that evolution proceeds by accumulation of...
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