Article

ReadBouncer: Precise and Scalable Adaptive Sampling for Nanopore Sequencing

2022-02-02

Abstract excerpt

Nanopore sequencers allow targeted sequencing of interesting nucleotide sequences by rejecting other sequences from individual pores. This feature facilitates the enrichment of low-abundant sequences by depleting overrepresented ones in-silico. Existing tools for adaptive sampling either apply signal alignment, which cannot handle human-sized reference sequences, or apply read mapping in sequence space relying on...

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Literature Corpus work: 2e80ebdf-0b88-51dc-9e80-b8ebda1f7b89
DOI: 10.1101/2022.02.01.478636

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