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<i>Mycobacterium tuberculosis</i> SecA2-dependent activation of host Rig-I/MAVs signaling is not conserved in <i>Mycobacterium marinum</i>

2023-01-27

Abstract excerpt

<h4>ABSTRACT</h4> Retinoic acid inducible gene I (Rig-I) is a cytosolic pattern recognition receptor canonically described for its important role in sensing viral RNAs. Increasingly, bacterially-derived RNA from intracellular bacteria such as Mycobacterium tuberculosis , have been shown to activate the same host Rig-I/Mitochondrial antiviral sensing protein (MAVS) signaling pathway to drive a type-I interferon r...

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Literature Corpus work
2e3b8968-8a27-5dac-b1c4-85881feb778a
DOI
10.1101/2023.01.27.525853
Open publication

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