Article
A New ESX-1 Substrate in Mycobacterium marinum That Is Required for Hemolysis but Not Host Cell Lysis
5 Mar 2019
Abstract excerpt
Both Mycobacterium tuberculosis , the cause of human tuberculosis (TB), and Mycobacterium marinum , a pathogen of ectotherms, use the ESX-1 secretion system to cause disease. There are many established similarities between the ESX-1 systems in M. tuberculosis and in M. marinum . Yet the two bacteria infect different hosts, hinting at species-specific functions of the ESX-1 system. Our findings demonstrate that...
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