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Article

An Essential Two-Component Signal Transduction System in <i>Mycobacterium tuberculosis</i>

1 Jul 2000

Abstract excerpt

The bacterial two-component signal transduction systems regulate adaptation processes and are likely to play a role in Mycobacterium tuberculosis physiology and pathogenesis. The previous initial characterization of an M. tuberculosis response regulator from one of these systems, mtrA-mtrB, suggested its transcriptional activation during infection of phagocytic cells. In this work, we further characterized the...

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Identifiers

PMID: 10851001
DOI: 10.1128/jb.182.13.3832-3838.2000

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