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Modulation of macrophage defense responses by Mycobacterial persistence protein MprA ( <i>Rv0981</i> ) in human THP-1 cells: effect of single amino acid variation on host-pathogen interactions

2020-04-28

Abstract excerpt

<h4>Summary</h4> M. tuberculosis is one of the most successful human pathogens causing tuberculosis that leads to highest daily morbidity worldwide. The evasion of the host immune responses is an important strategy that M. tuberculosis adopts. MprA ( Rv0981 ), the response regulator of two component system is known for DNA binding activity in the pathogen and its role in persistent infection in the host. MprA i...

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Literature Corpus work
22007771-706b-560a-995f-8d2a5e0a5d88
DOI
10.1101/2020.04.27.063602
Open publication

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Modulation of macrophage defense responses by Mycobacterial persistence protein MprA ( <i>Rv0981</i> ) in human THP-1 cells: effect of single amino acid variation on host-pathogen interactionsDOI 10.1101/2020.04.27.063602
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