Article

Deciphering the Role of the PAI_1-mBDNF Pathway in Alcohol Use Disorder: Insights into Pathogenesis and Abstinence Treatment Efficacy

2024-05-28

Abstract excerpt

<title>Abstract</title> <p>The pathway of plasminogen activator inhibitor-1 (PAI_1) -brain-derived neurotrophic factor (BDNF) plays a pivotal role in the conversion of Probrain-derived neurotrophic factor (ProBDNF) to mature BDNF (mBDNF), yet its clinical relevance in patients with alcohol use disorder remains understudied (AUD). Enzyme-linked immunosorbent assay (ELISA) was applied to examine the relevant protei...

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Literature Corpus work: 2e3ac575-1e6f-5aaf-9916-34162e6961fa
DOI: 10.21203/rs.3.rs-4387391/v1

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