Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human tissue-type plasminogen activator.

Thrombosis and haemostasis - 1 Aug 2014

Kruithof E K O, Dunoyer-Geindre S

Abstract excerpt

Tissue-type plasminogen activator (t-PA ) plays an important role in the removal of intravascular fibrin deposits and has several physiological roles and pathological activities in the brain. Its production by many other cell types suggests that t-PA has additional functions outside the vascular and central nervous system. Activity of t-PA is regulated at the level of its gene transcription, its mRNA stability...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Epigenesis, Genetic
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Protein Processing, Post-Translational

Share to Signal Transduction

Share to Tissue Plasminogen Activator

Share to Transcription, Genetic

Source

Identifiers

PMID: 24718307
DOI: 10.1160/TH13-06-0517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human tissue-type plasminogen activator.PMID 24718307Read ↗

The plasminogen activator system: biology and regulationSemantic proximity Read ↗

Three Decades of Research on Plasminogen Activator Inhibitor-1: A Multifaceted SerpinSemantic proximity Read ↗

The structural basis for the pathophysiological relevance of PAI-1 in cardiovascular diseases and the development of potential PAI-1 inhibitorsSemantic proximity Read ↗

Historical analysis of PAI-1 from its discovery to its potential role in cell motility and diseaseSemantic proximity Read ↗

Structure-function relationships of plasminogen activator inhibitor-1 and its potential as a therapeutic agent.Semantic proximity Read ↗

Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system.Semantic proximity Read ↗

From Plasminogen to Plasmin: Role of Plasminogen Receptors in Human CancerSemantic proximity Read ↗

PlasminogenSemantic proximity Read ↗

The plasminogen (fibrinolytic) system.Semantic proximity Read ↗

The story of the serpin plasminogen activator inhibitor 1: is there any need for another mutant?Semantic proximity Read ↗

PAI-1, the Plasminogen System, and Skeletal MuscleSemantic proximity Read ↗

Hemostasis and alterations of the central nervous system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.