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A membrane-permeable small molecule biosensor accesses intractable cells and animals without genetic manipulation

2026-05-23

Abstract excerpt

<h4>ABSTRACT</h4> Fluorescent biosensors have proven valuable for revealing the spatio-temporal dynamics of protein conformation in live cells and animals. The great majority of biosensors are genetically encoded, but genetic encoding is difficult or impossible to apply in many cases, including cells or animals with poorly understood genomes, no DNA, or sensitive to manipulation. Using biosensors without genetic...

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Literature Corpus work
2e00ea47-8a99-5a8c-bd4a-d48877d94976
DOI
10.64898/2026.05.22.727289
Open publication

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A membrane-permeable small molecule biosensor accesses intractable cells and animals without genetic manipulationDOI 10.64898/2026.05.22.727289
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