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Article

SerpinB3 drives cancer stem cell survival in glioblastoma

2021-12-22

Abstract excerpt

Despite therapeutic interventions for glioblastoma (GBM), cancer stem cells (CSCs) drive recurrence. The precise mechanisms underlying CSC therapeutic resistance, namely inhibition of cell death, are unclear. We built on previous observations that the high cell surface expression of junctional adhesion molecule-A drives CSC maintenance and identified downstream signaling networks, including the cysteine protease i...

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Identifiers and source

Literature Corpus work
2dc327fa-beb3-5119-97bc-8e0383819264
DOI
10.1101/2021.12.21.473663
Open publication

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SerpinB3 drives cancer stem cell survival in glioblastomaDOI 10.1101/2021.12.21.473663
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