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Article

A Novel Role of BIRC3 in Stemness Reprogramming of Glioblastoma

28 Dec 2021

Abstract excerpt

Stemness reprogramming remains a largely unaddressed principal cause of lethality in glioblastoma (GBM). It is therefore of utmost importance to identify and target mechanisms that are essential for GBM stemness and self-renewal. Previously, we implicated BIRC3 as an essential mediator of therapeutic resistance and survival adaptation in GBM. In this study, we present novel evidence that BIRC3 has an essential...

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PMID: 35008722
DOI: 10.3390/ijms23010297

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