Article

Aortic regurgitation provokes phenotypic modulation of smooth muscle cells in the normal ascending aorta

2023-02-12

Abstract excerpt

<h4>Background</h4> Aortic complications are more likely to occur in patients with ascending aortic aneurysms and concomitant aortic regurgitation (AR). AR may have a negative impact on the aortic wall structure even in patients with tricuspid aortic valves and absence of aortic dilatation. It is unknown whether smooth muscle cell (SMC) changes are a feature of AR-associated aortic remodeling. <h4>Methods</h4> N...

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Literature Corpus work: 2d9db794-2992-506e-b3db-c799767dee27
DOI: 10.1101/2023.02.08.527682

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