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Article

Preservation of Smooth Muscle Cell Integrity and Function: A Target for Limiting Abdominal Aortic Aneurysm Expansion?

Cells - 19 Mar 2022

Clark Emily R, Helliwell Rebecca J, Bailey Marc A, Hemmings Karen E, Bridge Katherine I, Griffin Kathryn J, Scott D Julian A, Jennings Louise M, Riches-Suman Kirsten, Porter Karen E

Abstract excerpt

(1) Abdominal aortic aneurysm (AAA) is a silent, progressive disease with significant mortality from rupture. Whilst screening programmes are now able to detect this pathology early in its development, no therapeutic intervention has yet been identified to halt or retard aortic expansion. The inability to obtain aortic tissue from humans at early stages has created a necessity for laboratory models, yet it is...

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Share to Aortic Aneurysm, Abdominal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35326494
DOI: 10.3390/cells11061043
PMCID: PMC8947535

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