Article

A rare case of well-differentiated liposarcoma with CDK4 amplification but without MDM2 amplification

2022-07-06

Abstract excerpt

<h4>Background: </h4> Well-differentiated liposarcoma (WDL)/atypical lipomatous tumor (ALT) and dedifferentiated liposarcoma (DDL) together comprise the largest subgroup of liposarcomas, and constitute up to 20% of all soft tissue sarcomas. WDL shares a common genetic feature characterized by high-level amplifications in the chromosome 12q13-15 region which contains the murine double minute-2 (MDM2), cyclin-depend...

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Literature Corpus work: 2d5cce66-7409-5f59-8376-f320815238e4
DOI: 10.21203/rs.3.rs-1794905/v1

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