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Article

The novel role of MDM2 in the diagnosis and treatment of dedifferentiated liposarcoma

18 Oct 2024

Abstract excerpt

Dedifferentiated liposarcoma (DDLPS) is a subtype of liposarcoma that frequently occurs in the retroperitoneum. Approximately 10% of atypical lipomatous tumors/well-differentiated liposarcomas (ALTs/WDLPSs) are dedifferentiated, with one risk factor being a retroperitoneal location (1). DDLPS exhibits heterogeneous differentiation, including myogenic or osteosarcomatous/chondrosarcomatous elements (1). The...

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PMID: 39493445
DOI: 10.3389/fonc.2024.1466399

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