Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

27 Mar 2023

Abstract excerpt

Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) present with a complex phenotype and are associated with high mortality and multi-organ involvement. We sought to define the transcriptional landscape and molecular endotypes of AAVs and compare it to systemic lupus erythematosus (SLE). Methods: We performed whole blood mRNA sequencing from 30 patients with AAV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Otitis Media and Relapsing Polychondritis
Share to Systemic Lupus Erythematosus Research
Share to Vasculitis and related conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37051253
DOI: 10.3389/fimmu.2023.1072598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosusPMID 37051253Read ↗

A stronger type I interferon signature distinguishes ANCA-associated vasculitis phenotypes and predicts kidney prognosis.Semantic proximity Read ↗

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitisSemantic proximity Read ↗

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis.Semantic proximity Read ↗

Different Disease Endotypes in Phenotypically Similar Vasculitides Affecting Small-to-Medium Sized Blood Vessels.Semantic proximity Read ↗

Significant association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitisSemantic proximity Read ↗

Kidney whole-transcriptome profiling in primary antiphospholipid syndrome reveals complement, interferons and NETs-related gene expressionSemantic proximity Read ↗

Inflammatory and JAK-STAT Pathways as Shared Molecular Targets for ANCA-Associated Vasculitis and Nephrotic SyndromeSemantic proximity Read ↗

Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsetsSemantic proximity Read ↗

Neutrophil single-cell analysis identifies a uniquely primed subset and provides insights into predicting relapse of autoimmune small vessel vasculitisSemantic proximity Read ↗

Cardiovascular risk in ANCA-associated vasculitis: Monocyte phenotyping reveals distinctive signatures between serological subsets.Semantic proximity Read ↗

Classification of ANCA-associated vasculitis: differences based on ANCA specificity and clinicopathologic phenotype.Semantic proximity Read ↗

Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Update: Genetic Pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.