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Article

Investigation of betaine as a novel psychotherapeutic for schizophrenia

2019-04-19

Abstract excerpt

<h4>ABSTRACT</h4> Betaine is known to act against various biological stresses and its levels were reported to be decreased in schizophrenia patients. Using Chdh (a gene for betaine synthesis)-deficient mice and betaine-supplemented inbred mice, we assessed the role of betaine in psychiatric pathophysiology, and its potential as a novel psychotherapeutic, by leveraging metabolomics, behavioral-, transcriptomics a...

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Literature Corpus work
2d1ca056-7a3c-59eb-a3d5-4218ee1abf67
DOI
10.1101/614164
Open publication

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