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Article

One-carbon metabolism and schizophrenia: current challenges and future directions.

Trends in molecular medicine - 1 Dec 2009

Krebs M O, Bellon Alfredo, Mainguy Gaell, Jay T M, Frieling Helge

Abstract excerpt

Schizophrenia is a heterogeneous disease generally considered to result from a combination of heritable and environmental factors. Although its pathophysiology has not been fully determined, biological studies support the involvement of several possible components including altered DNA methylation, abnormal glutamatergic transmission, altered mitochondrial function, folate deficiency and high maternal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19896901
DOI: 10.1016/j.molmed.2009.10.001

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