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Article

Redox dysregulation in the pathophysiology of schizophrenia and bipolar disorder: insights from animal models.

Antioxidants & redox signaling - 20 Apr 2013

Kulak Anita, Steullet Pascal, Cabungcal Jan-Harry, Werge Thomas, Ingason Andrés, Cuenod Michel, Do Kim Quang

Abstract excerpt

SIGNIFICANCE: Schizophrenia (SZ) and bipolar disorder (BD) are classified as two distinct diseases. However, accumulating evidence shows that both disorders share genetic, pathological, and epidemiological characteristics. Based on genetic and functional findings, redox dysregulation due to an imbalance between pro-oxidants and antioxidant defense mechanisms has been proposed as a risk factor contributing to...

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PMID: 22938092
DOI: 10.1089/ars.2012.4858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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