Article

Deanticoagulated Heparins Mediate Goblet Cell Differentiation to Restore Mucosal Barrier for Ulcerative Colitis Therapy

2026-02-13

Abstract excerpt

Mucosal barrier dysfunction is a pathological hallmark of ulcerative colitis (UC), yet current clinical therapeutic strategies remain predominantly limited to anti-inflammatory therapies and/or surgical treatment, lack of reliable treatment for mucosal repairment 1,2 . Here, through a systematic screen of our established library for deanticoagulated heparins 3 , we found that the nonanticoagulant low-molecular-w...

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Literature Corpus work: 2ce9d29e-fcd8-5db9-8c30-9f7097edc51f
DOI: 10.64898/2026.02.12.705304

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Deanticoagulated Heparins Mediate Goblet Cell Differentiation to Restore Mucosal Barrier for Ulcerative Colitis TherapyDOI 10.64898/2026.02.12.705304Read

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