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Molecular structure, expression, and functional role of Clec11a in skeletal biology and cancers

31 Jan 2020

Abstract excerpt

C-type lectin domain family 11 member A (Clec11a), also known as stem cell growth factor (SCGF), C-type lectin superfamily member 3 (CLECSF3), or osteolectin was initially identified as a growth factor for hematopoietic progenitor cells. The human Clec11a gene encodes a polypeptide of 323 amino acids with characteristics of a secreted glycoprotein encompassing two integrin-binding motifs, RGD (Arg-Gly-Asp) and...

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PMID: 32003015
DOI: 10.1002/jcp.29600

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