Article

NKD1 targeting PCM1 regulates the therapeutic effects of HHT on colorectal cancer cells

2023-04-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Colorectal cancer (CRC) is the most common primary malignancy. Homoharringtonine (HHT) has potential therapeutic effects on solid tumors. However, the regulatory target and mechanism of HHT in CRC progression remain elusive. <bold>Methods: </bold>CCK-8, Edu staining, flow cytometry and Western blotting assay to detect the effect of HHT on proliferation and apopt...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8e180062-bab1-52dd-b0f9-387341cf7874
DOI: 10.21203/rs.3.rs-2739531/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NKD1 targeting PCM1 regulates the therapeutic effects of HHT on colorectal cancer cellsDOI 10.21203/rs.3.rs-2739531/v1Read

NKD1 targeting PCM1 regulates the therapeutic sensitivity of HHT on colorectal cancer cellsSemantic proximity Read

The Role and Regulation of the NKG2D/NKG2D Ligand System in CancerSemantic proximity Read

Bioinformatics analysis and experimental verification of NLRX1 as a prognostic factor for esophageal squamous cell carcinomaSemantic proximity Read

Epigenetic modulation elicits an NK cell-mediated immune response in urothelial carcinomaSemantic proximity Read

HPK1 inhibitor enhanced tumor response to anti-PD-1 immunotherapy in Non-Hodgkin lymphomaSemantic proximity Read

PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancerSemantic proximity Read

NKG2D Ligands–Critical Targets for Cancer Immune Escape and TherapySemantic proximity Read

A Review on Notch Signaling and Colorectal Cancer.Semantic proximity Read

The role of lncRNA NEAT1 in human cancer chemoresistanceSemantic proximity Read

Regulation of the PD-1/PD-L1 axis and NK cell dysfunction by exosomal miR-552-5p in gastric cancerSemantic proximity Read

Investigating the Susceptibility of Treatment-Resistant Oesophageal Tumours to Natural Killer Cell-Mediated Responses.Semantic proximity Read

EPDR1 correlates with immune cell infiltration in hepatocellular carcinoma and can be used as a prognostic biomarkerSemantic proximity Read