Article

Copy number signatures in cervical samples enable early detection of high-grade serous ovarian carcinoma

2025-04-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Ovarian cancer is often diagnosed in advanced stages, resulting in poor outcomes. There is an unmet need for a sensitive and specific screening tool for early-stage detection of ovarian cancer. <h4>Methods</h4> Recognizing that high-grade serous ovarian carcinoma (HGSC) is driven by copy number alterations (CNAs) and that tumor DNA can be detected in cervical samples, we an...

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Literature Corpus work: 2cdf3d75-a6f1-5c77-a1d3-8ce0b457330a
DOI: 10.1101/2025.04.23.25325778

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