Article

Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning

2022-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that six CSF biomarkers (β-amyloid, total/phosphorylated tau, NfL, YKL-40, and neurogranin) cluster into five principal components (PC), each representing statistically independe...

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Literature Corpus work: 2cd2288a-a9c7-59ab-ae6e-17fc745d8b4d
DOI: 10.1101/2022.08.02.22278185

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